5(S),15(S)-DiHETE is synthesized by 15-LO from 5(S)-HETE. It potentiates the degranulation of human PMNL in response to PAF, but not fMLP, calcium ionophore A23187, or LTB4. 5(S),15(S)-DiHETE is chemotactic for eosinophils with an ED50 value of 0.3 µM.
Molecular Weight:
336.472
CAS Number:
[82200-87-1]
Formula:
C20H32O4
Target:
Interleukin|||Others
T37650
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