JC-171, a selective inhibitor of the NLRP3 inflammasome, effectively inhibits LPS/ATP-induced interleukin-1beta (IL-1beta) release from J774A.1 macrophages with an IC50 of 8.45 µM[1].
Molecular Weight:
384.83
CAS Number:
[2112809-98-8]
Formula:
C16H17ClN2O5S
Target:
NOD-like Receptor (NLR)|||Others
T38106
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