Iromycin A is a bacterial pyridone metabolite that inhibits nitric oxide synthase (NOS) activity, with selectivity for NOS III (endothelial NOS) over NOS I (neuronal NOS). Iromycin metabolites and derivatives block NADH oxidation in beef heart submitochondrial particles (IC50 = 0.461 µM for iromycin A).
Molecular Weight:
303.44
CAS Number:
[213137-53-2]
Formula:
C19H29NO2
Target:
Others|||NO Synthase
T38230
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