TBK1/IKKepsilon-IN-4, a 6-aminopyrazolopyrimidine derivative, serves as a potent, selective inhibitor for TBK1 and IKKepsilon, demonstrating IC50 values of 13 nM and 59 nM, respectively. This compound exhibits significantly reduced activity, by 100- to 1000-fold, against other protein kinases, such as PDK1, PI3K family members, and mTOR[1].
Molecular Weight:
533.62
CAS Number:
[1381930-17-1]
Formula:
C28H35N7O4
Target:
Others|||IkappaB/IKK
T38263
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