Potent gamma-secretase inhibitor (IC50 values are 1.2 and 6.2 nM in whole cell and cell-free assays, respectively). Reduces Abeta in brain, CSF and plasma in mice and guinea pigs.
Molecular Weight:
651.48
CAS Number:
[1962925-29-6]
Formula:
C27H43Br2F2N5O
Target:
Apoptosis|||Others|||Gamma-secretase
T38266
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