Benzomalvin C is a weak antagonist of the neurokinin-1 (NK1) receptor, inhibiting binding of substance P by 46% at 100 µg/ml in vitro, and a weak inhibitor of indolamine 2,3-dioxygenase (IDO) with an IC50 value of 130 µM for recombinant IDO. Isolated from Penicillium, it contains an epoxide group at C-19 and C-20, absent in benzomalvins A, B, or E.
Molecular Weight:
395.418
CAS Number:
[157047-98-8]
Formula:
C24H17N3O3
Target:
Others|||Neurokinin receptor
T38276
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