Apramycin (Nebramycin II), CAS [[37321-09-8]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T38303
Supplier Catalog Number:
T38303
Alternative Catalog Number:
TGM-T38303-500MG
Manufacturer:
TargetMol
Category:
Biochemikalien
Apramycin(Nebramycin II) is an aminoglycoside antibiotic used in veterinary medicine.Target: Apramycin stands out among aminoglycosides for its mechanism of action which is based on blocking translocation and its ability to bind also to the eukaryotic decoding site despite differences in key residues required for apramycin recognition by the bacterial target. The drug binds in the deep groove of the RNA which forms a continuously stacked helix comprising non-canonical C.A and G.A base pairs and a bulged-out adenine. The binding mode of apramycin at the human decoding-site RNA is distinct from aminoglycoside recognition of the bacterial target, suggesting a molecular basis for the actions of apramycin in eukaryotes and bacteria.
Molecular Weight:
539.58
CAS Number:
[37321-09-8]
Formula:
C21H41N5O11
Target:
Antibiotic|||Antibacterial|||Others
T38303
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