ALK-IN-12 is a highly potent and orally active inhibitor of anaplastic lymphoma kinase (ALK), demonstrating an exceptional IC50 value of 0.18 nM. Additionally, ALK-IN-12 displays inhibitory activity against insulin-like growth factor 1 receptor (IGF1R) and insulin receptor (InsR), with IC50 values of 20.3 nM and 90.6 nM, respectively. Notably, its antitumor effects have been observed, making it a promising compound for targeted cancer therapy.
Molecular Weight:
500.97
CAS Number:
[1197958-53-4]
Formula:
C24H30ClN6O2P
Target:
Others|||ALK
T38584
* VAT and and shipping costs not included. Errors and price changes excepted
