Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced activation of MAPK and NF-kappaB. Isoliquiritin apioside auppresseses invasiveness and angiogenesis of cancer cells and endothelial cells. Isoliquiritin apioside has marked potential to combat oxidative stress-induced genotoxicity.
Molecular Weight:
550.51
Purity:
99.27%
CAS Number:
[120926-46-7]
Formula:
C26H30O13
Target:
MMP|||p38 MAPK|||NF-kappaB
T3860
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