Seco-DUBA is an anticancer DNA alkylating agent and prodrug of DUBA, which can be used as a cytotoxic antibody-drug conjugate (ADC). It has an IC50 of 18 nM against KB and 430 pM against SK-OV-3, and can be converted into DUBA with higher stability and activity in vivo.
Molecular Weight:
526.97
Purity:
99.81%
CAS Number:
[1227961-59-2]
Formula:
C29H23ClN4O4
Target:
ADC Cytotoxin|||DNA Alkylation
T38611
T38611
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