Irigenin mediates its antimetastatic effect by specifically and selectively blocking the alpha9beta1 and alpha4beta1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enhancing the expression of pro-apoptotic molecules in gastric cancer cells and has anti-cancer effects.
Molecular Weight:
360.31
Purity:
99.50%
CAS Number:
[548-76-5]
Formula:
C18H16O8
Target:
Integrin|||Apoptosis|||NF-kappaB
T3862
* VAT and and shipping costs not included. Errors and price changes excepted
