AP 811, a selective antagonist of the atrial natriuretic peptide clearance receptor (APN-CR, NPR3) with a K i value of 0.48 nM, exhibits remarkable selectivity for NPR3 over NPR1 by more than 20,000-fold. Moreover, AP 811 effectively eliminates ANP-induced pump stimulation.
Molecular Weight:
915.11
CAS Number:
[124833-45-0]
Formula:
C46H66N12O8
Target:
Natriuretic peptide
T38641
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