SR-1277 is a potent, highly selective and ATP-competitive CK1delta/epsilon inhibitor with IC50 values of 49 nM and 260 nM, respectively.CK1delta plays a crucial role in regulating Wee1 activity at the G2/M cell-cycle interface, and exhibits significant antiproliferative activity against a variety of cancer cells.
Molecular Weight:
477.5
CAS Number:
[1446715-47-4]
Formula:
C21H19N9O3S
Target:
Casein Kinase
T38927
T38927
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