(3R,5S)-Fluvastatin, the 3R,5S-isomer of Fluvastatin (XU 62-320 free acid), stands as the inaugural fully synthetic, competitive inhibitor of HMG-CoA reductase, exhibiting an IC50 value of 8 nM. It safeguards vascular smooth muscle cells from oxidative stress by activating the Nrf2-dependent antioxidant pathway.
Molecular Weight:
411.47
CAS Number:
[155229-75-7]
Formula:
C24H26FNO4
Target:
Others|||Autophagy|||HMG-CoA Reductase
T39036
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