GS-493, a highly specific protein tyrosine phosphatase SHP2 (PTPN11) inhibitor, exhibits remarkable potency with an IC50 of 71 nM. It displays 29- and 45-fold greater affinity towards SHP2 compared to its related counterparts, SHP1 and PTP1B, respectively. In addition, GS-493 impedes both cellular motility and growth of cancer cells, portraying promising antitumor effects.
Molecular Weight:
510.44
CAS Number:
[1710337-31-7]
Formula:
C21H14N6O8S
Target:
Others|||Phosphatase
T39167
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