(3S, 4S)-PF-06459988 is the less active S enantiomer of PF-06459988, a potent irreversible inhibitor of T790M mutant epidermal growth factor receptor (EGFR), exhibiting excellent selectivity against EGFR wild-type due to its minimally reactive electrophile, reducing off-target labeling likelihood.
Molecular Weight:
431.88
CAS Number:
[1858291-14-1]
Formula:
C19H22ClN7O3
Target:
Others|||EGFR
T39299
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