Zetomipzomib maleate (KZR-616), a novel immunoproteasome inhibitor, effectively and selectively inhibits the LMP7 subunit (hLMP7/mLMP7 IC50: 39/57 nM) and LMP2 subunit (hLMP7/mLMP7 IC50: 131/179 nM) of the immunoproteasome. This compound shows promising potential for research in various autoimmune diseases.
Molecular Weight:
702.758
CAS Number:
[2170983-62-5]
Formula:
C34H46N4O12
Target:
Others|||Proteasome
T39653
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