ATG7-IN-1 is a highly potent, selective small-molecule ATG7 inhibitor with an IC50 of 62 nM. ATG7-IN-1 blocks the formation of the ATG12-ATG5 and LC3-PE conjugate system at both the cellular and in vivo levels, thereby inhibiting autophagosome formation. ATG7-IN-1 can be used in research on autophagy mechanisms.
Molecular Weight:
470.5
Purity:
99.85%
CAS Number:
[2226229-87-2]
Formula:
C17H19FN6O5S2
Target:
ATG|||Autophagy
T39705
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