Crelosidenib is a potent and selective mutant IDH inhibitor with IC50s of 6.27 nM, 3.71 nM, 36.9 nM, and 11.5 nM for IDH1 R132H, IDH1 R132C, IDH2 R140Q, and IDH2 R172K mutases, respectively, and low inhibitory activity against the wild-type IDH enzyme.
Molecular Weight:
504.62
Purity:
98.54%
CAS Number:
[2230263-60-0]
Formula:
C28H36N6O3
Target:
Isocitrate Dehydrogenase (IDH)|||Dehydrogenase
T39716
T39716
* VAT and and shipping costs not included. Errors and price changes excepted
