Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium concentration. Ryanodine receptors mediate the release of calcium from the sarcoplasmic reticulum, an essential step in muscle contraction. Dantrolene sodium hemiheptahydrate (Sodium dantrolene) is the sodium salt form of dantrolene, a hydantoin derivative, and direct-acting skeletal muscle relaxant.
Molecular Weight:
399.29
Purity:
98.52%
CAS Number:
[24868-20-0]
Formula:
C14H9N4NaO53.5H2O
Target:
Calcium Channel|||Apoptosis|||ROS|||Autophagy
T4054
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