NH-3 is a potent orally active thyroid hormone receptor (THR) antagonist which exhibits reversible behavior, demonstrated by an IC 50 of 55 nM. Derived from the selective thyromi-metic GC-1, NH-3 effectively inhibits the binding of thyroid hormones to their respective receptors, resulting in hindered cofactor recruitment.
Molecular Weight:
473.52
Purity:
97.09%
CAS Number:
[447415-26-1]
Formula:
C28H27NO6
Target:
Thyroid hormone receptor(THR)
T40548
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