Thiocolchicine is an effective inhibitor of tubulin polymerization with an IC50 of 2.5 µM and a Ki of 0.7 µM. Thiocolchicine induces cell apoptosis. Thiocolchicine can be used as an ADC cytotoxin in ADC technology.
Molecular Weight:
415.5
Purity:
98.19%
CAS Number:
[2730-71-4]
Formula:
C22H25NO5S
Target:
Apoptosis|||Microtubule Associated
T41248
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