AZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrant EGFR inhibitor. At Km ATP concentrations, the IC50s are 0.2/0.3/0.2 nM for EGFR (L858R)/EGFR (wt)/EGFR (exon 19Del).
Molecular Weight:
496.36
Purity:
99.62%
CAS Number:
[1626387-81-2]
Formula:
C22H24Cl2FN5O3
Target:
Apoptosis|||EGFR
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