Prexasertib (LY2606368) is a selective checkpoint kinase 1 (CHK1) inhibitor (Ki 0.9 nM, IC50<1 nM). Prexasertib causes double-stranded DNA breaks and replication mutations, leading to apoptosis. Prexasertib has antitumor activity.
Molecular Weight:
365.39
Purity:
97.28%
CAS Number:
[1234015-52-1]
Formula:
C18H19N7O2
Target:
Chk|||Apoptosis
T4310
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