Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 µM for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. Reduces growth of TDO-expressing P815 mastocytoma tumors in mice. Orally bioavailable.
Molecular Weight:
229.21
Purity:
98.78%
CAS Number:
[1316695-35-8]
Formula:
C11H8FN5
Target:
Others|||Indoleamine 2,3-Dioxygenase (IDO)|||IDO
T4410
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