Tucidinostat (Chidamide) is an effective and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8/11 (IC50: 733/432 nM), and shows no effect on HDAC4/5/6/7/9.
Molecular Weight:
390.41
Purity:
97.01%
CAS Number:
[1616493-44-7]
Formula:
C22H19FN4O2
Target:
HDAC
T4481
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