1. Pristimerin (Celastrol methyl ester) has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell characteristics and EMT in cancer cells. 2. Pristimerin down-regulates the expression of pro-inflammatory mediators through blocking of NF-kappaB activation by inhibiting interconnected ROS/IKK/NF-kappaB signaling pathways, can effectively inhibit both arthritic inflammation and cartilage and bone damage in the joints.
Molecular Weight:
464.64
Purity:
98.59%
CAS Number:
[1258-84-0]
Formula:
C30H40O4
Target:
NF-kappaB|||Antibacterial
T4S1050
* VAT and and shipping costs not included. Errors and price changes excepted
