Coptisine, CAS [[3486-66-6]]

Product Overview

• Article Name: Coptisine, CAS [[3486-66-6]]
• Biozol Catalog Number: TGM-T5S0053
• Supplier Catalog Number: T5S0053
• Alternative Catalog Number: TGM-T5S0053-1MLX10MM(INDMSO),TGM-T5S0053-1MG,TGM-T5S0053-5MG,TGM-T5S0053-10MG,TGM-T5S0053-25MG,TGM-T5S0053-50MG,TGM-T5S0053-100MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: Coptisin

Product Description

1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial apoptosis and inflammation by inhibiting the Rho/ROCK pathway. 3. Coptisine is a potential anti-osteosarcoma drug candidate, via exerting a strong anti-osteosarcoma effect with very low toxicity . 4. Coptisine with a high dosage could inhibit cholesterol synthesis via suppressing the HMGCR expression and promoting the use and excretion of cholesterol via up-regulating LDLR and CYP7A1 expression. 5. Coptisine suppresses adhesion, migration and invasion of MDA-MB-231 breast cancer cells in vitro, the down-regulation of MMP-9 in combination with the increase of TIMP-1 possibly contributing to the anti-metastatic function for breast cancer.

Product Properties

• Molecular Weight: 320.32
• Purity: 98.00%
• CAS Number: [3486-66-6]
• Formula: C19H14NO4
• Target: IDO|||Indoleamine 2,3-Dioxygenase (IDO)|||LDLR

Images

T5S0053