(1S,2R)-Alicapistat ((1S,2R)-ABT-957) is a highly efficient, orally active compound that selectively inhibits human calpains 1 and 2, showing promise for Alzheimers disease (AD) therapy [1]. It effectively addresses the metabolic liability associated with carbonyl reduction and demonstrates potent inhibition of calpain 1 with an IC50 value of 395 nM [2].
Molecular Weight:
433.5
Purity:
98.05%
CAS Number:
[2221010-57-5]
Formula:
C25H27N3O4
Target:
Proteasome|||Cysteine Protease
T60150
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