TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) agonist (EC50: 7.39). It shows higher affinity for FFAR1 or GPR40 relative to related receptors FFA2, FFA3, and the nuclear receptor PPARgamma, as well as various other receptors, ion channels, and transporter proteins. TUG-499 is useful for studying Type 2 diabetes.
Molecular Weight:
320.17
Purity:
99.59%
CAS Number:
[1206629-08-4]
Formula:
C16H11Cl2NO2
Target:
GPCR|||PPAR
T60184
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