Metallo-beta-lactamase-IN-6 is a highly effective inhibitor of VIM-Type metallo-beta-lactamase, demonstrating IC50 values of 0.56 µM, 29.50 µM, and 5.78 µM for VIM-2, VIM-1, and VIM-5, respectively. Additionally, Metallo-beta-lactamase-IN-6 exhibits potent synergistic antibacterial properties when combined with Meropenem, particularly against engineered Escherichia coli strains and clinically isolated Pseudomonas aeruginosa carrying the VIM-2 MBL gene [1].
Molecular Weight:
203.2
CAS Number:
[1439899-44-1]
Formula:
C10H9N3O2
Target:
Antibacterial|||Others
T60239
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