Collagen-IN-1 (compound 3) is an ortho-carbonyl hydroquinone derivative that selectively inhibits collagen. It non-competitively inhibits agonist-induced platelet aggregation, with an IC50 value of 1.77 µM. Collagen-IN-1 reduces P-selectin expression, glycoprotein IIb/IIIa activation, and the release of adenosine triphosphate and CD63 from platelets. This compound is promising for research into platelet-related thrombosis diseases [1].
Molecular Weight:
230.26
CAS Number:
[104260-73-3]
Formula:
C14H14O3
Target:
Others
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