CCR4 antagonist 3-1, CAS [[1957-01-3]]

Product Overview

• Article Name: CCR4 antagonist 3-1, CAS [[1957-01-3]]
• Biozol Catalog Number: TGM-T60336
• Supplier Catalog Number: T60336
• Alternative Catalog Number: TGM-T60336-1MG,TGM-T60336-5MG,TGM-T60336-10MG,TGM-T60336-25MG,TGM-T60336-50MG,TGM-T60336-100MG,TGM-T60336-500MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

CCR4 antagonist 3-1 is a less active chemokine receptor 4 (CCR4) antagonist that inhibits [125I]TARC (thymus and activation-regulated chemokine) with an IC50 value of 1.7 µM. CCR4 antagonist 3-1 inhibits the binding of radiolabeled [125I]TARC and macrophage-derived chemokine ( MDC) to CEM cell surface and inhibits TARC-mediated CEM cell migration in vitro with an IC50 value of 6.4 µM. CCR4 antagonist 3 inhibited the binding of radiolabeled [125I]TARC and macrophage-derived chemokine (MDC) to the CCR4 receptor on the surface of CEM cells and inhibited TARC-mediated migration of CEM cells in vitro with an IC50 value of 6.4 µM.

Product Properties

• Molecular Weight: 240.32
• Purity: 99.53%
• CAS Number: [1957-01-3]
• Formula: C14H12N2S
• Target: CCR

Images

T60336