LY367385 hydrochloride is a potent and selective mGluR1a antagonist with an IC50 value of 8.8 µM for inhibiting quisqualate-induced phosphoinositide (PI) hydrolysis, showing significantly higher selectivity compared to its >100 µM IC50 value for mGlu5a. This compound exhibits neuroprotective, anticonvulsant, and antiepileptic effects [1] [2].
Molecular Weight:
245.66
CAS Number:
[2829282-00-8]
Formula:
C10H12ClNO4
Target:
Others|||GluR
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