TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1.
Molecular Weight:
547.96
Purity:
0.9973
CAS Number:
[871026-44-7]
Formula:
C26H25ClF3N5O3
Target:
MEK|||EGFR|||Aurora Kinase|||HER
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