JMS-053 is a potent and selective inhibitor of the phosphatase DUSP3, inhibits PTP4A3, PTP4A1, PTP4A2 and CDC25B, inhibits cancer cell migration and sphere growth, and avoids disruption of the microvascular endothelial barrier by vascular endothelial growth factor or lipopolysaccharide.
Molecular Weight:
256.28
Purity:
98.0%
CAS Number:
[1954650-11-3]
Formula:
C13H8N2O2S
Target:
Ras|||STAT|||Phosphatase
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