CAY10789, CAS [[123226-28-8]]

Product Overview

• Article Name: CAY10789, CAS [[123226-28-8]]
• Biozol Catalog Number: TGM-T60439
• Supplier Catalog Number: T60439
• Alternative Catalog Number: TGM-T60439-1MG,TGM-T60439-5MG,TGM-T60439-10MG,TGM-T60439-25MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

CAY10789 (compound 6) is a potent CysLT1R (cysteinyl leukotriene receptor 1) antagonist with an IC50 of 2.80 µM and a GPBAR1 (G-protein-coupled bile acid receptor 1) agonist with an EC50 of 3 µM. It significantly decreases U937 cell adhesion to HAEC and reduces TNF-alpha expression. CAY10789 demonstrates promising metabolic stability and excellent pharmacokinetics, making it suitable for studying colitis, metabolic syndromes, and other GPBAR1/CysLT1R-related diseases [1].

Product Properties

• Molecular Weight: 265.31
• CAS Number: [123226-28-8]
• Formula: C17H15NO2
• Target: Others|||GPCR19|||TNF|||Leukotriene Receptor

Images

T60439