NLRP3/AIM2-IN-3, CAS [[1787787-60-3]]

Product Overview

• Article Name: NLRP3/AIM2-IN-3, CAS [[1787787-60-3]]
• Biozol Catalog Number: TGM-T60442
• Supplier Catalog Number: T60442
• Alternative Catalog Number: TGM-T60442-1MLX10MM(INDMSO),TGM-T60442-5MG,TGM-T60442-10MG,TGM-T60442-25MG,TGM-T60442-50MG,TGM-T60442-100MG,TGM-T60442-500MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

NLRP3/AIM2-IN-3 is a unique molecule that inhibits NLRP3 and AIM2 inflammasome activation in a species-specific manner. It has an IC50 value for cell lysis of 0.077 0.008 µ M. NLRP3/AIM2-IN-3 is a potent inhibitor of NLRP3 and AIM2 inflammasome-dependent cell lysis with an IC50 value for cell lysis of 0.077 0.008 µ M. NLRP3/AIM2-IN-3 inhibits LPS/nigericin NLRP3/AIM2-IN-3 inhibits LPS/nigericin-stimulated cell lysis in THP-1 macrophages with an IC50 value of 0.077 0.008 µM. NLRP3/AIM2-IN-3 interferes with the interaction of NLRP3 or AIM2 with the bridging protein ASC, inhibiting oligomerization of ASC.

Product Properties

• Molecular Weight: 266.29
• Purity: 97.16%
• CAS Number: [1787787-60-3]
• Formula: C16H14N2O2
• Target: NOD|||NOD-like Receptor (NLR)|||Pyroptosis|||AIM2

Images

T60442