DIF-3 is a chemical compound that acts by activating GSK-3beta to facilitate the degradation of cyclin D1 and c-Myc, resulting in reduced expression levels of these proteins. In addition, DIF-3 inhibits Wnt/beta-catenin signaling pathway-related proteins in DLD-1 cells. This compound exerts a potent antiproliferative effect on the HeLa human cervical cancer cell line by inducing cyclin D1 degradation and inhibiting cyclin D1 mRNA expression [1].
Molecular Weight:
272.72
Purity:
99.57%
CAS Number:
[113411-17-9]
Formula:
C13H17ClO4
Target:
CDK|||Wnt/beta-catenin|||GSK-3
T60485
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