DDO-7263 is a 1,2,4-Oxadiazole derivative that upregulates Nrf2 through binding to Rpn6 to block the assembly of 26S proteasome and the subsequent degradation of ubiquitinated Nrf2. DDO-7263 is a potent Nrf2 activator that activates the Nrf2-ARE signaling pathway and exerts anti-inflammatory activity [1].
Molecular Weight:
273.24
Purity:
99.85%
CAS Number:
[2254004-96-9]
Formula:
C14H9F2N3O
Target:
Nrf2
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