CDK1/2/4-IN-1 (compound 3a) is a potent CDK inhibitor with IC50 values of 1.47, 0.78, and 0.87 µM for CDK1, CDK2, and CDK4, respectively. It can be used in cancer research to arrest the cell cycle at the G2/M phase and induce apoptosis, elevating Bax, caspase-3, and P53 levels while decreasing Bcl-2 levels [1].
Molecular Weight:
288.36
CAS Number:
[2414633-49-9]
Formula:
C15H16N2O2S
Target:
Caspase|||Bcl-2 Family|||Apoptosis|||Others|||CDK
T60583
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