Topoisomerase I inhibitor 2 (ZML-8) is a highly selective DNA topoisomerase I (Top1) inhibitor that impedes Top1 activity, causing DNA damage. It arrests the cell cycle at the G2/M phase and induces apoptosis, exhibiting anti-tumor effects [1].
Molecular Weight:
293.32
CAS Number:
[2588211-44-1]
Formula:
C18H15NO3
Target:
Topoisomerase|||Others|||Apoptosis|||Caspase
T60617
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