ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively. It is more than 8-fold selective for Aurora A/B than MEK1, Src, Lck and has little effect against CDK1/2/4, Plk1, Chk1, etc.
Molecular Weight:
513.59
Purity:
99.59%
CAS Number:
[331771-20-1]
Formula:
C29H31N5O4
Target:
Src|||MEK|||Aurora Kinase|||Apoptosis
T6077
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