THK-5117 is an arylquinoline derivative with the potential as a PET probe for tau imaging. THK-5117 shows high binding affinity to tau fibrils with a Ki value of 10.5 nM. THK-5117 also shows high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD) brain homogenates [1].
Molecular Weight:
326.36
CAS Number:
[1374107-54-6]
Formula:
C19H19FN2O2
Target:
Others|||Microtubule Associated
T60907
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