PDE4-IN-9 (Compound 5j) is a potent PDE4 inhibitor with an IC50 value of 1.4 µM against PDE4 in vitro enzyme assays, which is lower than the 2.0 µM of parent rolipram, and demonstrates good in vivo activity in LPS-induced animal models of asthma/COPD and sepsis [1].
Molecular Weight:
328.35
CAS Number:
[2519450-32-7]
Formula:
C15H12N4O3S
Target:
Others|||PDE
T60934
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