Izuforant (JW1601) (Compound 24) exhibits potent anti-inflammatory and anti-pruritic activities, with a binding affinity for human serotonin 3 receptor (h5-HT3R) and an IC50 value of 9.1 µM. It is also an orally active antagonist of histamine H4 receptor (H4R), showing an IC50 value of 36 nM against human H4R [1] [2].
Molecular Weight:
334.17
CAS Number:
[1429374-83-3]
Formula:
C12H12BrN7
Target:
Others|||Histamine Receptor
T61011
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