Piribedil hydrochloride can be used in the parkinsons disease, circulatory disorders, cancers research. Piribedil hydrochloride inhibits MLL1 methyltransferase activity with EC50 value of 0.18 µM. Piribedil hydrochloride is a potent and orally active agonist of dopamine D2 and dopamine D3 as well as the antagonist of alpha2-adrenoceptors [1] [2] [3] [4].