Topoisomerase I/II inhibitor 2 (compound 1a) is a DNA topoisomerase I/II dual inhibitor that significantly reduces xenograft tumor growth in a mouse model, indicating its potential use in treating liver cancer. It is a potent topoisomerase inhibitor with IC50 values of 6.83 µM and 9.82 µM for LM9 cells and Huh7 cells [1].
Molecular Weight:
336.34
Formula:
C19H16N2O4
Target:
Topoisomerase|||Others
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