UCB-5307 is a small molecule compound that inhibits TNFR1 signal transduction and downstream function in vitro. The KD of human TNFalpha is 9 nM. The TNF was directly bound by slow binding kinetics,KD= 6 nM. UCB-5307 can pass through prefabricated hTNF/hTNFR1 complexes.
Molecular Weight:
343.42
Purity:
0.9989
CAS Number:
[1515887-44-1]
Formula:
C22H21N3O
Target:
TNF
T61111
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