Metallo-beta-lactamase-IN-5 (compound 5c) is a potent inhibitor of metallo-beta-lactamases (MBLs), demonstrating inhibitory activity against MBLs NDM-1 and VIM-1. It effectively inhibits HUVECs with an IC50 value of 45 µg/mL. Additionally, when combined with Imipenem, Metallo-beta-lactamase-IN-5 exhibits synergistic antimicrobial activity [1].
Molecular Weight:
348.36
CAS Number:
[1417737-65-5]
Formula:
C19H16N4O3
Target:
Apoptosis|||Others|||Antibacterial
T61173
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